Analysis the efficacy of moringa oleifera leaf supplementation on reducing iron deficiency anemia
DOI:
https://doi.org/10.35335/midwifery.v14i4.2471Keywords:
Adolescent Girls, Flood Disaster, Iron Deficiency Anemia, Hemoglobin Level, Moringa OleiferaAbstract
Natural disasters, particularly severe flooding, frequently impair local food security and healthcare access, severely aggravating iron deficiency anemia (IDA) among adolescent girls. Although post-disaster humanitarian aid often addresses basic caloric intake, specific micronutrient vulnerabilities in adolescents remain critically neglected, while standard synthetic iron supplements suffer from low adherence due to gastrointestinal side effects. This study aimed to analyze the efficacy of controlled Moringa oleifera leaf powder capsule supplementation in reducing IDA cases among menstruating adolescent girls eight months post-flood disaster in Aceh Tamiang Regency. Utilizing a quasi-experimental one-group pretest-posttest design in Lhok Medang Ara Village, baseline screening of 187 menstruating girls aged 10–15 years identified 103 anemic individuals (prevalence 55.08%, baseline hemoglobin [Hb] < 12.0 g/dL). All 103 anemic subjects received a controlled daily oral dosage of 1,000 mg Moringa leaf powder capsules (2 × 500 mg/day after meals) for 30 consecutive days. Hemoglobin concentrations were measured at baseline (Day 0) and post-intervention (Day 30) using a calibrated digital hemoglobinometer and analyzed using paired sample t-tests. Results demonstrated a statistically and clinically significant elevation in mean Hb from 10.22 ± 0.74 g/dL pre-intervention to 11.97 ± 0.68 g/dL post-intervention (p = 0.000), representing a mean Hb rise of 1.75 g/dL (range 1.50–2.00 g/dL) and restoring normal Hb status (≥ 12.0 g/dL) in 86.41% (n = 89) of subjects. In conclusion, controlled Moringa oleifera supplementation represents an effective, highly tolerable nutraceutical green medicine strategy to alleviate post-disaster IDA, offering vital support for community midwifery health recovery programs
Downloads
References
Abdelrahman, M. M., Alhidary, I. A., Aljumaah, R. S., & Faye, B. (2022). Blood Trace Element Status in Camels: A Review. Animals, 12(16), 2116. https://doi.org/10.3390/ani12162116
Astuti, Y., & Idealistiana, L. (2024). Efektivitas teh daun kelor terhadap peningkatan Hb pada remaja putri dengan anemia. Jurnal Kesehatan Malahayati, 8(2), 2644–2651. https://doi.org/https://doi.org/10.33024/mnj.v6i7.11418
Azizah, D. I. (2020). Asupan Zat Besi, Asam Folat, dan Vitamin C pada Remaja Putri di Daerah Jatinangor. Jurnal Kesehatan Vokasional, 4(4), 169. https://doi.org/10.22146/jkesvo.46425
Cavalcoli, F., Gandini, A., Matelloni, I. A., Catalano, F., Alicante, S., Manfredi, G., Brambilla, G., Menozzi, F., Perolini, F., Costi, E., Bertè, R., & Buscarini, E. (2020). Dietary iron intake and anemia: food frequency questionnaire in patients with hereditary hemorrhagic telangiectasia. Orphanet Journal of Rare Diseases, 15(1), 1–6. https://doi.org/10.1186/s13023-020-01554-x
Concise Guide to Hematology. (2019). In H. M. Lazarus & A. H. Schmaier (Eds.), Concise Guide to Hematology (2nd ed.). Springer. https://doi.org/10.1007/978-3-319-97873-4_39
Dewi, N. U., Khomsan, A., Dwiriani, C. M., Riyadi, H., & Ekayanti, I. (2023). Nutritional literacy improvement and its impact on the dietary quality of adolescents in food-insecure households post-disaster. Journal of Nutrition and Food Security, 8(3), 312–320.
Fauziandri, E. N. (2019). Efektifitas ekstrak daun kelor terhadap peningkatan kadar hemoglobin pada remaja putri. Jurnal Kesehatan Karya Husada, 7(2), 15–22. https://doi.org/https://doi.org/10.36577/jkkh.v7i2.230
Greer, J. P., Rodgers, G. M., Glader, B., Arber, D. A., Means JR, R. T., List, A. F., Appelbaum, F. R., Dispenzieri, A., & Fehniger, T. A. (2019). Wintrobe’s Clinical Hematology. In Wintrobe’s Clinical Hematology (14th ed.). Wolters Kluwer.
Grober, U. (2012). Mikronutrien : Penyelarasan Metabolik, Pencegahan dan Terapi. EGC.
Hall, J. E., & Guyton, A. C. (2011). Guyton and Hall : Textbook of Medical Physiology (12th ed.). Saunders Elsevier.
Hardisman. (2021). Tanya Jawab Metodologi Penelitian Kesehatan (Referensi Praktis Mahasiswa S1, S2, S3, PPDS dan Peneliti Pemula. Gosyen Publishing.
Hidayati, Y., Sulastri, D., & Defrin, D. (2024). Analisis Faktor Risiko Anemia Defisiensi Besi pada Remaja Putri. Plexus Medical Journal, 3(4), 172–191.
Khani Jeihooni, A., Hoshyar, S., Afzali Harsini, P., & Rakhshani, T. (2021). The effect of nutrition education based on PRECEDE model on iron deficiency anemia among female students. BMC Women’s Health, 21(1), 1–9. https://doi.org/10.1186/s12905-021-01394-2
Khare, A., Samudre, S., & Arora, A. (2022). Sneak-peek into iron deficiency anemia in India : The need for food-based interventions and enhancing iron bioavailability. Food Research International, 162(PA), 111927. https://doi.org/10.1016/j.foodres.2022.111927
Kumar, S. B., Arnipalli, S. R., Mehta, P., Carrau, S., & Ziouzenkova, O. (2022). Iron Deficiency Anemia: Efficacy and Limitations of Nutritional and Comprehensive Mitigation Strategies. Nutrients, 14(14). https://doi.org/10.3390/nu14142976
Mirani, N., Syahida, A., & Khairurrozi, M. (2021). Prevalensi Anemia Defisiensi Besi pada Remaja Putri di Kota Langsa. Media Publikasi Promosi Kesehatan Indonesia (MPPKI), 4(2), 132–137. https://doi.org/10.56338/mppki.v4i2.1486
Moorthy, D., Merrill, R., Namaste, S., & Iannotti, L. (2020). The Impact of Nutrition-Specific and Nutrition-Sensitive Interventions on Hemoglobin Concentrations and Anemia: A Meta-review of Systematic Reviews. Advances in Nutrition, 11(6), 1631–1645. https://doi.org/10.1093/advances/nmaa070
Murray, R. K., Granner, D. K., & Rodwell, V. W. (2006). Biokimia HARPER (27th ed.). EGC.
Notoatmodjo, P. D. S. (2018). Metodologi Penelitian Kesehatan (Cet. 3). Rineka Cipta.
Notoatmodjo, S. (2014). Metodologi Penelitian Kesehatan. Jakarta: Rineka Cipta.
Sari, A. P., & Nurhayati, E. (2023). Dampak bencana alam terhadap status gizi dan kejadian anemia pada kelompok rentan di daerah terdampak. Jurnal Kebencanaan Dan Kesehatan, 4(2), 101–110.
Setiadi, S. A. I. S. A. W. (2014). Buku Ajar Ilmu Penyakit Dalam Jilid 1 Edisi 6 / Editor, Siti Setiadi ...[et al.]. //lib.fkik.untad.ac.id/index.php?p=show_detail&id=1300
Shubham, K., Anukiruthika, T., Dutta, S., Kashyap, A. V., Moses, J. A., & Anandharamakrishnan, C. (2020a). Iron deficiency anemia: A comprehensive review on iron absorption, bioavailability and emerging food fortification approaches. Trends in Food Science and Technology, 99(February), 58–75. https://doi.org/10.1016/j.tifs.2020.02.021
Shubham, K., Anukiruthika, T., Dutta, S., Kashyap, A. V., Moses, J. A., & Anandharamakrishnan, C. (2020b). Iron deficiency anemia: A comprehensive review on iron absorption, bioavailability and emerging food fortification approaches. Trends in Food Science and Technology, 99, 58–75. https://doi.org/10.1016/j.tifs.2020.02.021
Skolmowska, D. (2022). Effectiveness of Dietary Intervention with Iron and Vitamin C Administered Separately in Improving Iron Status in Young Women. 1–19.
Sugiyono. (2019). Metode Penelitian Kuantitatif Kualitatif. Alfabeta.
Suryadinata, P. Y. A., Suega, K., Wayan, I., & Dharmayuda, T. G. (2022). Faktor Risiko Yang Mempengaruhi Kejadian Anemia Defisiensi Besi : A Systematic Review. Jurnal Medika Udayana, 11(2), 6–12.
Vallet, N., Delaye, J. B., Ropert, M., Foucault, A., Ravalet, N., Deriaz, S., Chalopin, T., Blasco, H., Maillot, F., Hérault, O., & Gyan, E. (2021). Megaloblastic anemia-related iron overload and erythroid regulators: a case report. Journal of Medical Case Reports, 15(1), 1–5. https://doi.org/10.1186/s13256-021-03065-0
World Health Organization. (2020a). WHO guidance helps detect iron deficiency and protect brain development.
World Health Organization. (2020b). WHO Guideline O Use of Ferritin Concentrations to Assess Iron Status in Individuals and Populations.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Yusmalia Hidayati, Wiwiek Elsada Nainggolan, Fransisca Kotsasi

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.


