The influence of sodium and leukocyte levels as predictor factors in pediatric perforated appendicitis at bhayangkara tk. i pusdokkes police hospital
DOI:
https://doi.org/10.35335/midwifery.v10i6.1172Keywords:
Appendicitis with perforation, Area Under Curve(AUC), Cut OffAbstract
Acute appendicitis is an inflammation of the appendix, the part of the small intestine located in the lower right side of the abdomen. This is a severe medical condition that usually requires surgery emergency. The main symptoms of acute appendicitis include abdominal pain radiating to the lower right side, fever, and nausea. This study aims to determine the role of sodium and leukocytes as predictors of perforated appendicitis in children at Bhayangkara Tk. I Pusdokkes Police Hospital. This concept is expected to help the readers understand how sodium level and leukocyte count can predict the likelihood of children's perforated appendicitis. This study is important for improving the diagnosis and treatment of children with perforated appendicitis. The study's results through a total sample of 52 participants showed significant differences in sodium and leukocyte levels in patients with a diagnosis of perforated appendicitis and appendicitis without perforation. This was proven by the results of testing using the Mann-Whitney differential test, which obtained a significance value for Na levels of 0.049 and leukocyte levels of 0.000. These values were smaller than the p-value of 0.05. The accuracy of the diagnosis of leukocyte levels is shown through two AUC values (Area Under the Curve) of 0.747 or 74.7%. This value is greater than 70% and indicates very good accuracy. Meanwhile, the AUC value for sodium levels is only 0.229 or 22.9%, so it is considered less accurate. The Cut Off value for Na levels was 132.50 mEq/liter, while leukocytes were 13.715/microliter of blood.
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References
Dickinson, C. M., Coppersmith, N. A., & Luks, F. I. (2017). Early Predictors of Abscess Development after Perforated Pediatric Appendicitis. Surgical Infections, 18(8), 886–889. https://doi.org/10.1089/sur.2017.134
Duman, L., Karaibrahimoğlu, A., Büyükyavuz, B. I., & Savaş, M. Ç. (2022). Diagnostic value of monocyte-to-lymphocyte ratio against other biomarkers in children with appendicitis. Pediatric Emergency Care, 38(2), E739–E742. https://doi.org/10.1097/PEC.0000000000002347
KemenKes. (2019). Laporan Riskesdas 2018. Jakarta: Kementerian Kesehatan RI.
Lesmana, G. P., Rudiman, R., & Septrina, R. (2020). Accuracy of D-Dimer Levels and C-reactive Protein in Predicting Perforation of Acute Appendicitis. Jurnal Llmu Bedah Indonesia, 48(1), 59–69. https://doi.org/10.46800/jibi-ikabi.v48i1.57
Lindestam, U., Almström, M., Jacks, J., Malmquist, P., Lönnqvist, P. A., Jensen, B. L., Carlström, M., Krmar, R. T., Svensson, J. F., Norberg, Å., & Fläring, U. (2020). Low Plasma Sodium Concentration Predicts Perforated Acute Appendicitis in Children: A Prospective Diagnostic Accuracy Study. European Journal of Pediatric Surgery, 30(4), 350–356. https://doi.org/10.1055/s-0039-1687870
Lui, A.F., Smith, J., Chen, Y., & Johnson, R. (2021). Appendicities: Diagnosis and Management. Journal of Surgical Techniques, 56, 967–972. https://doi.org/10.1016/j.jss.2021.06.054
McLauthlin, C. H., & Packard, G. B. (2017). Acute appendicitis in children. The American Journal of Surgery, 101(5), 619–625. https://doi.org/10.1016/0002-9610(61)90272-0
S., C., M. G., L., & S. R., A. (2018). Prevalence of perforated appendicitis and its determinants in pediatric appendicitis patients admitted in tertiary care centre, South India: a cross sectional study. International Surgery Journal, 5(12), 3926. https://doi.org/10.18203/2349-2902.isj20185020
Shimoda, M., Maruyama, T., Nishida, K., Suzuki, K., Tago, T., Shimazaki, J., & Suzuki, S. (2018). Comparison of clinical outcome of laparoscopic versus open appendectomy, single center experience. Heliyon, 4(5), e00635. https://doi.org/10.1016/j.heliyon.2018.e00635
Simpson, J., & Scholefield, J. H. (2013). Acute appendicitis. Foundation Years, 2(2), 72–75. https://doi.org/10.1053/S1744-1889(06)70056-1
Smith J. (2019). Acute appendicitis and perforation (20th ed.). Philadelphia, PA: Elsevier.
Sugiyono. (2017). Metode Penelitian Kuantitatif, Kualitatif (R & D). Bandung: CV Alfabeta.
Sugiyono. (2018). Metode Penelitian Kuantitatif.
Sugiyono. (2019). Metode Penelitian Kuantitatif, Kualitatif, dan R&D (1st ed.). Penerbit Alfabeta.
Sukmawati E, wahyunita yulia sari, & indah sulistyoningrum. (2018). Farmakologi Kebidanan. Trans Info Media (TIM). https://scholar.google.com/scholar?oi=bibs&cluster=11760770443894442881&btnI=1&hl=id
Vaos, G., Dimopoulou, A., Gkioka, E., & Zavras, N. (2019). Immediate surgery or conservative treatment for complicated acute appendicitis in children? A meta-analysis. Journal of Pediatric Surgery, 54(7), 1365–1371. https://doi.org/10.1016/j.jpedsurg.2018.07.017
WHO. (2020). Director-General’s opening remarks at the media briefing on COVID-19 - 11 March 2020.
Yang, J., Liu, C., He, Y., & Cai, Z. (2019). Laboratory Markers in the Prediction of Acute Perforated Appendicitis in Children. Emergency Medicine International, 2019, 1–4. https://doi.org/10.1155/2019/4608053
Zvizdic, Z., Jonuzi, A., Djuran, A., & Vranic, S. (2019). Gastric necrosis and perforation following massive gastric dilatation in an adolescent girl: A rare cause of acute abdomen. Frontiers in Surgery, 6. https://doi.org/10.3389/fsurg.2019.00003
