The effectiveness comparison of appendectomy action through the antibiotic therapy administration in acute appendicitis patients
DOI:
https://doi.org/10.35335/midwifery.v11i1.1208Keywords:
Antibiotics, Appendectomy, AppendicitisAbstract
The purpose of this research to compare the effectiveness of appendectomy by administering non-operative management in the form of antibiotics in acute appendicitis patients. The research method used descriptive qualitative through the Literature Review (LR) approach. The data source used a secondary source. Data analysis technique selects literature based on title, year, and indexed articles, then reviews articles that match the subject matter. the articles from those journals are compared to find the differences and similarities. A literature review of four PubMed, DOAJ, Cochrane, and Google Scholar databases published in the last five years, i.e. from 2018-2022. Twelve pieces of literature were obtained and reported the advantages and disadvantages of each procedure. Apshortextomy keeps the gold standard with a lower risk of recurrence and severity and a higher treatment success rate. Appendectomy is also required for appendicitis cases with complications. However, antibiotic therapy has advantages with lower levels of complications, fewer costs, and fewer hospital stays. The success rate of non-operative therapy in the form of antibiotics can reach 65-75%, while it can reach 67,1% in children. There are differences in research results related to the effectiveness of appendectomy and antibiotic therapy in acute appendicitis patients. Each of these therapeutic procedures has its advantages and disadvantages. It is very important to be concerned about the urgency and expectations of the patient in selecting this therapy.
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References
Awayshih, M. M. Al, Nofal, M. N., & Yousef, A. J. (2019). Evaluation of alvarado score in diagnosing acute appendicitis. Pan African Medical Journal, 34. https://doi.org/10.11604/pamj.2019.34.15.17803
Bi, L. W., Yan, B. L., Yang, Q. Y., & Cui, H. L. (2019). Comparison of conservative treatment with appendectomy for acute uncomplicated pediatric appendicitis: A meta-analysis. Journal of Comparative Effectiveness Research, 8(10), 767–780. https://doi.org/10.2217/cer-2019-0036
Bom, W. J., Scheijmans, J. C. G., Salminen, P., & Boermeester, M. A. (2021). Diagnosis of Uncomplicated and Complicated Appendicitis in Adults. In Scandinavian Journal of Surgery (Vol. 110, Issue 2). https://doi.org/10.1177/14574969211008330
Ceresoli, M., Coccolini, F., Magnone, S., Lucianetti, A., Bisagni, P., Armao, T., Ansaloni, L., Zago, M., Chiarugi, M., Catena, F., Braga, M., Nizzardo, M., Nespoli, L., Fattori, L., Degrate, L., Perrone, S., Cereda, M., Pisano, M., Poiasina, E., … Fugazzola, P. (2021). The decrease of non-complicated acute appendicitis and the negative appendectomy rate during pandemic. European Journal of Trauma and Emergency Surgery, 47(5). https://doi.org/10.1007/s00068-021-01663-7
Chisthi, M. M., Surendran, A., & Narayanan, J. T. (2020). RIPASA and air scoring systems are superior to alvarado scoring in acute appendicitis: Diagnostic accuracy study. Annals of Medicine and Surgery, 59. https://doi.org/10.1016/j.amsu.2020.09.029
Flum & Davidson. (2021). A Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis. New England Journal of Medicine, 384(9), 879–881. https://doi.org/10.1056/nejmc2035865
Haijanen, J., Sippola, S., Tuominen, R., Gronroos, J., Paajanen, H., Rautio, T., Nordstrom, P., Aarnio, M., Rantanen, T., Hurme, S., & Salminen, P. (2019). Cost analysis of antibiotic therapy versus appendectomy for treatment of uncomplicated acute appendicitis: 5-year results of the APPAC randomized clinical trial. PLoS ONE, 14(7). https://doi.org/10.1371/journal.pone.0220202
Herrod, P. J. J., Kwok, A. T., & Lobo, D. N. (2022). Randomized clinical trials comparing antibiotic therapy with appendicectomy for uncomplicated acute appendicitis: meta-analysis. BJS Open, 6(4). https://doi.org/10.1093/bjsopen/zrac100
Köhler, F., Acar, L., van den Berg, A., Flemming, S., Kastner, C., Müller, S., Diers, J., Germer, C. T., Lock, J. F., L’hoest, H., Marschall, U., & Wiegering, A. (2021). Impact of the COVID-19 pandemic on appendicitis treatment in Germanyâ€â€Âa population-based analysis. Langenbeck’s Archives of Surgery, 406(2). https://doi.org/10.1007/s00423-021-02081-4
McLauthlin, C. H., & Packard, G. B. (2017). Acute appendicitis in children. The American Journal of Surgery, 101(5), 619–625. https://doi.org/10.1016/0002-9610(61)90272-0
Minneci, P. C., Hade, E. M., Lawrence, A. E., Sebastião, Y. V., Saito, J. M., Mak, G. Z., Fox, C., Hirschl, R. B., Gadepalli, S., Helmrath, M. A., Kohler, J. E., Leys, C. M., Sato, T. T., Lal, D. R., Landman, M. P., Kabre, R., Fallat, M. E., Cooper, J. N., & Deans, K. J. (2020). Association of nonoperative management using antibiotic therapy vs laparoscopic appendectomy with treatment success and disability days in children with uncomplicated appendicitis. JAMA - Journal of the American Medical Association, 324(6), 581–593. https://doi.org/10.1001/jama.2020.10888
Moraga, F., Ahumada, V., & Crovari, F. (2016). Are antibiotics a safe and effective treatment for acute uncomplicated appendicitis? Medwave, 16, e6375. https://doi.org/10.5867/medwave.2015.6375
O’Leary, D. P., Walsh, S. M., Bolger, J., Baban, C., Humphreys, H., O’Grady, S., Hegarty, A., Lee, A. M., Sheehan, M., Alderson, J., Dunne, R., Morrin, M. M., Lee, M. J., Power, C., McNamara, D., McCawley, N., Robb, W., Burke, J., Sorensen, J., & Hill, A. D. (2021). A Randomized Clinical Trial Evaluating the Efficacy and Quality of Life of Antibiotic-only Treatment of Acute Uncomplicated Appendicitis: Results of the COMMA Trial. Annals of Surgery, 274(2), 240–247. https://doi.org/10.1097/SLA.0000000000004785
Patkova, B., Svenningsson, A., Almström, M., Eaton, S., Wester, T., & Svensson, J. F. (2020). Nonoperative treatment versus appendectomy for acute nonperforated appendicitis in children: Five-year follow up of a randomized controlled pilot trial. Annals of Surgery, 271(6), 1030–1035. https://doi.org/10.1097/SLA.0000000000003646
Poprom, N., Numthavaj, P., Wilasrusmee, C., Rattanasiri, S., Attia, J., McEvoy, M., & Thakkinstian, A. (2019). The efficacy of antibiotic treatment versus surgical treatment of uncomplicated acute appendicitis: Systematic review and network meta-analysis of randomized controlled trial. American Journal of Surgery, 218(1), 192–200. https://doi.org/10.1016/j.amjsurg.2018.10.009
Prechal, D., Damirov, F., Grilli, M., & Ronellenfitsch, U. (2019). Antibiotic therapy for acute uncomplicated appendicitis: a systematic review and meta-analysis. International Journal of Colorectal Disease, 34(6), 963–971. https://doi.org/10.1007/s00384-019-03296-0
Rushing, A., Bugaev, N., Jones, C., Como, J. J., Fox, N., Cripps, M., Robinson, B., Velopulos, C., Haut, E. R., & Narayan, M. (2019). Management of acute appendicitis in adults: A practice management guideline from the Eastern Association for the Surgery of Trauma. Journal of Trauma and Acute Care Surgery, 87(1). https://doi.org/10.1097/TA.0000000000002270
Shimoda, M., Maruyama, T., Nishida, K., Suzuki, K., Tago, T., Shimazaki, J., & Suzuki, S. (2018). Comparison of clinical outcome of laparoscopic versus open appendectomy, single center experience. Heliyon, 4(5), e00635. https://doi.org/10.1016/j.heliyon.2018.e00635
Smith J. (2019). Acute appendicitis and perforation (20th ed.). Philadelphia, PA: Elsevier.
Snapiri, O., Rosenberg Danziger, C., Krause, I., Kravarusic, D., Yulevich, A., Balla, U., & Bilavsky, E. (2020). Delayed diagnosis of paediatric appendicitis during the COVID-19 pandemic. Acta Paediatrica, International Journal of Paediatrics, 109(8). https://doi.org/10.1111/apa.15376
Vaos, G., Dimopoulou, A., Gkioka, E., & Zavras, N. (2019). Immediate surgery or conservative treatment for complicated acute appendicitis in children? A meta-analysis. Journal of Pediatric Surgery, 54(7), 1365–1371. https://doi.org/10.1016/j.jpedsurg.2018.07.017
Yang, Z., Sun, F., Ai, S., Wang, J., Guan, W., & Liu, S. (2019). Meta-analysis of studies comparing conservative treatment with antibiotics and appendectomy for acute appendicitis in the adult. BMC Surgery, 19(1). https://doi.org/10.1186/s12893-019-0578-5
