Relationship between the use of antibiotics and anti-pain in breast cancer patients (ca mammae)

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Mohamad Rizky
Lidya Angelina Rotua
Windiyani Nur'amanah Suharmin
Ratni Kaino
Defita Zubaidi

Abstract

The most common cancer detected in women is breast cancer. After lung cancer, it is the most frequent reason for cancer-related mortality. This is because patients who have advanced breast cancer seek medical attention. The lack of understanding about breast cancer and how to do breast self-examination (BSE) for early identification of breast cancer among the general population contributed to the delay in treatment. This research aimed to ascertain how patients with Camamae used antib iotics and painkillers in connection to one another. This kind of research is retrospective, descriptive, and utilizes secondary data. Patients diagnosed with breast cancer between January 2019 and December 2023 were selected from medical records at the Regional General Hospital dr. Hasri Ainun Habibie as a research subject. The results obtained from medical records show that the relationship between painkillers and antibiotics is very important where giving painkillers to breast cancer patients is to improve the patient's quality of life, especially for patients who have experienced arrest or removal of breast tissue while giving antibiotics is to prevent exposure to bacteria when it will be carried out profit and after done.

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How to Cite
Rizky, M., Rotua, L. A., Suharmin, W. N., Kaino, R. and Zubaidi, D. (2023) “Relationship between the use of antibiotics and anti-pain in breast cancer patients (ca mammae)”, Science Midwifery, 11(4), pp. 721-731. doi: 10.35335/midwifery.v11i4.1361.

References

Abdullah, M., & Gunawan, J. (2012). Functional Dispepsia. Divisi Gastroentrologi, Bagian Ilmu Penyakit Dalam.
Aidah, S. N., & Tim Penerbit KBM Indonesia. (2021). Cara Sembuh 100% Dari Kanker Payudara Keajaiban Sarang Semut Papua (F. Setiawan (ed.)). CV. Karya Bakti Makmur Indonesia.
Aisyah, E., & Nadjib, M. (2019). Evaluasi Ekonomi Penggunaan Antibiotika Profilaksis Cefotaxime dan Ceftriaxone pada Pasien Operasi Seksio Sesarea di Rumah Sakit X. Jurnal Ekonomi Kesehatan Indonesia, 3(2), 57–67. https://doi.org/10.7454/eki.v3i2.3160
Amelia, K., Sumarny, R., Hasan, D., Komar, H., & Pola, K. (2019). Kajian Pola Penggunaan Antibiotik Profilaksis Dan Diagnosa Pascaoperasi Hubungannya Dengan Angka Kejadian Infeksi Daerah Operasi (IDO) Pada Pasien Bedah Digestif Di Rumah Sakit Swasta. Jurnal Ilmiah Kedokteran, 6(1), 104–112.
Arshad, H. M., Mohiuddin, O. A., & Azmi, M. B. (2012). Comparative In Vitro Antibacterial Analysis Of Different Brands Of Cefixime Against Clinical Isolates Of Staphylococcus Aureus And Escherichia Coli. Journal of Applied Pharmaceutical Science, 2(1), 109–113.
Banadji, Y. M. (2019). Perbandingan Efektivitas Metamizol 15 mg/KgBB IV dengan Asetaminofen 15 mg/KgBB IV untuk Analgesia Pasca-Bedah di Bawah Umbilikus pada Pasien Pediatrik Comparison. Universitas Indonesia.
Black, J. M., & Hawks, J. H. (2014). Keperawatan Medikal Bedah: Manajemen Klinis Untuk Hasil Yang Diharapkan (8th ed.). Elsevier Singapura.
BPOM RI. (2015, November). Drug For Patient Safety. Buletin Berita Meso.
Caliskan, E., Sener, M., Kocum, A., Ozyilkan, N. B., Ezer, S. S., & Aribogan, A. (2013). The Efficacy Of Intravenous Paracetamol Versus Dipyrone For Postoperative Analgesia After Day-Case Lower Abdominal Surgery In Children With Spinal Anesthesia: A Prospective Randomized Double-Blind Placebo-Controlled Study. BMC Anesthesiology, 13(1), 1–8. https://doi.org/10.1186/1471-2253-13-34
Cardoso, F., Kyriakides, S., Ohno, S., Penault-Llorca, F., Poortmans, P., Rubio, I. T., Zackrisson, S., & Senkus, E. (2019). Early breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncology, 30(8), 1194–1220. https://doi.org/10.1093/annonc/mdz173
de Leeuw, T. G., Dirckx, M., Gonzalez Candel, A., Scoones, G. P., Huygen, F. J. P. M., & de Wildt, S. N. (2017). The Use Of Dipyrone (Metamizol) As An Analgesic In Children: What Is The Evidence? Paediatric Anaesthesia, 27(12), 1193–1201. https://doi.org/10.1111/pan.13257
Dewi, R. (2021). Teknik Relaksasi Lima Jari Terhadap Kualitas Tidur, Fatique dan Nyeri Pada Pasien Kanker Payudara. Deepublish Publisher.
Edy, A. J., & Nugroho, T. E. (2019). Pengaruh Pemberian Analgesik Kombinasi Paracetamol Dan Morfin Terhadap Kreatinin Serum Pada Tikus Wistar Jantan. Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal), 8(1), 8–19. https://doi.org/10.14710/dmj.v8i1.23292
Fadilah, P. N., Astuti, P., & Santy, W. H. (2018). Pengaruh Teknik Relaksasi Hand Massage Terhadap Nyeri Pada Pasien Kanker Payudara Di Yayasan Kanker Indonesia Surabaya. Journal of Health Sciences, 9(2), 221–226. https://doi.org/10.33086/jhs.v9i2.171
Ferreira-Valente, M. A., Pais-Ribeiro, J. L., & Jensen, M. P. (2011). Validity Of Four Pain Intensity Rating Scales. Pain®, 152(10), 2399–2404. https://doi.org/10.1016/j.pain.2011.07.005
Gilman, A. G. (2012). Dasar Farmakologi Terapi (J. G. Hardman & L. E. Limbird (eds.); 10th ed.). Penerbit Buku Kedokteran EGC.
Glare, P. A., Davies, P. S., Finlay, E., Gulati, A., Lemanne, D., Moryl, N., Oeffinger, K. C., Paice, J. A., Stubblefield, M. D., & Syrjala, K. L. (2014). Pain in Cancer Survivors. Journal of Clinical Oncology, 32(16), 1739–1747. https://doi.org/10.1200/JCO.2013.52.4629
Harahap, N. I. (2019). Penggunaan Antibiotik pada Penyakit Infeksi Saluran Kemih di RSU Datu Beru Takengon. JIFI (Jurnal Ilmiah Farmasi Imelda), 2(2), 69–74.
Hero, S. K. (2021). Faktor Risiko Kanker Payudara. Jurnal Medika Hutama, 3(1), 1533–1537.
Hudyarisandi, W. (2016). Efektivitas Kombinasi Tramadol Dan Paracetamol Oral Sebagai Preemptive Analgesia Terhadap Nyeri Intraoperatif Dan Pascaoperatif Pada Pasien Yang Menjalani Operasi Dengan Anastesinumum Di Gedung Bedah Pusat Terpadu RSUD DR. Soetomo Surabaya. Airlangga university Surabaya.
Huzaimah, N., & Pratiwi, I. G. D. (2020). Studi Fenomenologi: Pengalaman Orang dengan HIV/AIDS (ODHA) yang Menjalani Terapi Antiretroviral. Jurnal Ilmiah Kesehatan, 2(1), 19–29. https://doi.org/10.36590/jika.v2i1.47
Ihsan, M., Kurniawati, F., Khoirunnisa, H., & Chairini, B. (2019). Evaluation of Pain Scale Decrease and Adverse Effects of Ketorolac Injections: An Observational Study in Patients with Postoperative Pain. Indonesian Journal of Pharmacy, 30(2), 133–140. https://doi.org/10.14499/indonesianjpharm30iss2pp133-140
Iqmy, L. O., Setiawati, S., & Yanti, D. E. (2021). Faktor Risiko Yang Berhubungan Dengan Kanker Payudara. Jurnal Kebidanan Malahayati, 7(1), 32–36. https://doi.org/10.33024/jkm.v7i1.3581
Katzung, B. G. (2018). Basic & Clinical Pharmacology. In Basic and clinical Pharmacology (14th ed.). Mcgraw-Hill Education.
Lovell, A. R., & Ernst, M. E. (2017). Drug-Induced Hypertension: Focus on Mechanisms and Management. Current Hypertension Reports, 19, 1–12. https://doi.org/10.1007/s11906-017-0736-z
Marek, C. L., & Timmons, S. R. (2019). Antimicrobials in Pediatric Dentistry. In Pediatric Dentistry (pp. 128–141). Elsevier. https://doi.org/10.1016/b978-0-323-60826-8.00009-2
Maria, I. L., Sainal, A. A., & Nyorong, M. (2017). Gaya Hidup Terhadap Kejadian Kanker Payudara Pada Wanita. Media Kesehatan Masyarakat Indonesia, 13(2), 157–166. https://doi.org/10.30597/mkmi.v13i2.1988
Maryunani, A. (2016). Perawatan Luka Modern (Modern Wound Care) Terkini dan Terlengkap sebagai Bentuk Tindakan Keperawatan Mandiri. In Media.
Mittal, S., Sharma, A., Sharma, A., Gupta, K., Gaur, A., & Pathania, V. (2018). Banded Versus Single-Sided Bonded Space Maintainers: A Comparative Study. Indian Journal of Dental Sciences, 10(1), 29–36. https://doi.org/10.4103/ijds.ijds_76_17
Momenimovahed, Z., & Salehiniya, H. (2019). Epidemiological Characteristics Of And Risk Factors For Breast Cancer In The World. Breast Cancer: Targets and Therapy, 151–164. https://doi.org/10.2147/BCTT.S176070
Nurhayati, N., Arifin, Z., & Hardono, H. (2019). Analisis Faktor-Faktor Yang Berhubungan Dengan Kejadian Kanker Payudara (Studi Retrospektif) Di Lampung, Indonesia. Holistik Jurnal Kesehatan, 13(2), 172–183.
Nurrohmah, A., Aprianti, A., & Hartutik, S. (2022). Risk Factors of Breast Cancer. Gaster Journal Of Health Science, 20(1), 1–10. https://doi.org/10.30787/gaster.v20i1.777
Pachman, D. R., Barton, D. L., Swetz, K. M., & Loprinzi, C. L. (2012). Troublesome Symptoms in Cancer Survivors: Fatigue, Insomnia, Neuropathy, and Pain. Journal of Clinical Oncology, 30(30), 3687–3696. https://doi.org/10.1200/JCO.2012.41.7238
Paice, J. A., & Ferrell, B. (2011). The Management Of Cancer Pain. CA: A Cancer Journal For Clinicians, 61(3), 157–182. https://doi.org/10.3322/caac.20112
Permata, V. A., Nurcahyo, W. I., & Supatmo, Y. (2014). Penggunaan Analgesik Pasca Operasi Orthopedi Di Rsup Dr. Kariadi Semarang. Jurnal Kedokteran Diponegoro, 3(1), 116199.
Purwidyaningrum, I., Peranginangin, J. M., & Mardiyono, J. S. (2019). Dagusibu, Pertolongan Pertama Pada Kecelakaan di Rumah dan Penggunaan Antibiotik Secara Rasional Di Kelurahan Nusukan. Journal of Dedicators Community UNISNU Jepara, 3(1), 23–43.
Raphael, J., Hester, J., Ahmedzai, S., Barrie, J., Farqhuar-Smith, P., Williams, J., Urch, C., Bennett, M. I., Robb, K., Simpson, B., Pittler, M., Wider, B., Ewer-Smith, C., DeCourcy, J., Young, A., Liossi, C., McCullough, R., Rajapakse, D., Johnson, M., … Sparkes, E. (2010). Cancer Pain: Part 2: Physical, Interventional and Complimentary Therapies; Management in the Community; Acute, Treatment-Related and Complex Cancer Pain: A Perspective from the British Pain Society Endorsed by the UK Association of Palliative Medicine and. Pain Medicine, 11(6), 872–896. https://doi.org/10.1111/j.1526-4637.2010.00841.x
Satoto, D., Rahendra, Mujahidin, Imai Indra, & Rifky Jamal. (2020). Perbandingan Efektivitas Analgesik Oral Controlled Release Oksikodon 10 Mg dan Parasetamol 1000 Mg dengan Tramadol 50 Mg dan Parasetamol 1000 Mg dalam Mengatasi Nyeri Pascaseksio Sesarea. Majalah Anestesia & Critical Care, 38(3), 155–167. https://doi.org/10.55497/majanestcricar.v38i3.206
Schumacher, M. A., Balani, P., Min, J., Chinnam, N. B., Hansen, S., Vulić, M., Lewis, K., & Brennan, R. G. (2015). HipBA–Promoter Structures Reveal The Basis Of Heritable Multidrug Tolerance. Nature, 524(7563), 59–64. https://doi.org/10.1038/nature14662
Syahputra, P. R., & Nugroho, T. E. (2017). Pengaruh Pemberian Analgesik Kombinasi Parasetamol Dan Tramadol Terhadap Kadar Serum Glutamat Piruvat Transaminase. Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal), 6(2), 1035–1042. https://doi.org/10.14710/dmj.v6i2.18615
Syamsu, A. S. I. (2017). Monitoring Efek Samping Dan Efektivitas Terapi Ketorolak Dan Metamizol Pada Pasien Cedera Kepala Di Rsup Dr. Wahidin Sudirohusodo Makassar. Universitas Hasanuddin Makassar.
Syarif, A., Gayatri, A., Estuningtyas, A., Setiawati, A., Muchtar, H. A., Arif, A., Rosdiana, D. S., Suyatna, F. D., Dewoto, H. R., Utama, H., Instiaty, Louisa, M., Biomed, M., Wiria, M. S. S., Nafrialdi, Wilmana, P. F., Ascobat, P., Setiabudy, R., Suherman, S. K., … Sadikin, Z. D. (2016). Farmakologi dan Terapi (S. G. Gunawan, R. Setiabudy, Nafrialdi, & Instiaty (eds.); 6th ed.). Departemen Farmakologi dan Terapeutik fakultas Kedokteran Universitas Indonesia.
Tjay, T. H., & Rahardja, K. (2015). Obat-Obat Penting: Khasiat Penggunaan dan Efek - Efek Sampingnya. PT Elex Media Komputindo.
Tooley, A., & Vickers, H. (2014). The Adverse Effects Of Intravenous Ketorolac Related To Postoperative Hemorrhage And Hematoma In Adults Aged 18 Years And Older: A Systematic Review Protocol. JBI Database of Systematic Reviews and Implementation Reports, 12(6), 3–12. https://doi.org/10.11124/jbisrir-2014-1531
Vitaloka, N. R., Susanti, R., & Yuswar, A. (2019). Efektivitas Penggunaan Antibiotik Profilaksis Pada Pasien Bedah Sesar (Sectio Caesarea) Di Rumah Sakit Umum Daerah Dr. Rubini Mempawah. Jurnal Mahasiswa Farmasi Fakultas Kedokteran UNTAN, 5(1).
Wulandari, A., & Purba, E. M. (2019). Analisis Biaya Minimum Penggunaan Antibiotik Ceftriaxone dan Cefotaxime Pada Penderita Diare Akut Anak di RSUD dr. Chasbullah Abdulmadjid Periode Januari–Desember 2017. Sainstech Farma: Jurnal Ilmu Kefarmasian, 12(1), 39–43. https://doi.org/10.37277/sfj.v12i1.416
Yasa, I. N. P., Kresnoadi, E., & Nandana, P. I. (2017). Efektifitas Tramadol dibandingkan Ketoprofen untuk Mengurangi Nyeri pada Pasien Pasca Operasi Bedah di RS. Bhayangkara menggunakan VAS skor. Unram Medical Journal, 6(2), 17–20. https://doi.org/10.29303/jku.v6i2.128