The effectiveness of narrowband ultraviolet b phototherapy for the treatment of moderate to severe psoriasis in adult patients

Authors

  • Hutami Rizki Rahmawati Universitas UPN Veteran Jakarta, Indonesia
  • Stephanie Deborah Djuanda Universitas Atma Jaya, Indonesia
  • Helena Azhar Ainun Universitas Yarsi, Indonesia
  • Shafira Aghnia Winditia Universitas Andalas, Indonesia
  • Devanie Martani Universitas Tarumanagara, Indonesia

DOI:

https://doi.org/10.35335/midwifery.v12i2.1517

Keywords:

Phototherapy, Psoriasis, Ultraviolet B

Abstract

Psoriasis is a chronic skin condition influenced by genetics and the environment. It affects 57.8 per 100.000 people in 2019. The severity of psoriasis is assessed using the Psoriasis Area Severity Index (PASI), with scores above 10 indicating moderate to severe disease. Treatment options for psoriasis including systemic therapies and phototherapy. Patient satisfaction remains suboptimal, with adherence rates to systemic therapy as low as 40%. Narrowband ultraviolet B (NB-UVB) phototherapy is preferred for its safety. This review aims to evaluate the effectiveness of NB-UVB phototherapy in treating moderate-to-severe psoriasis in adults. Descriptive analysis was the method that journal used, search of online databases was conducted and found 12 relevant articles meeting criteria, published in English between 2014 and 2024, focusing on patients with moderate to severe psoriasis receiving NB-UVB phototherapy. Our review found that NB-UVB phototherapy, whether used alone or in combination with adjuvants, effectively treats moderate to severe psoriasis vulgaris in adult patients. Combining NB-UVB with adjuvants can further improve its effectiveness. However, further research is needed to assess its effectiveness across different age groups and to optimize treatment strategies based on individual patient characteristics and disease severity.

Downloads

Download data is not yet available.

References

Ara, S., Mowla, M. R., Alam, M., & Khan, I. (2020). Efficacy of oral methotrexate (MTX) monotherapy vs oral MTX plus narrowband ultraviolet light B phototherapy in palmoplantar psoriasis. Dermatologic Therapy, 33(4). https://doi.org/10.1111/dth.13486

Çaliskan, E., Tunca, M., Açikgöz, G., Arca, E., Yürekli, A., & Akar, A. (2015). Narrow band ultraviolet-B versus Goeckerman therapy for psoriasis with and without acitretin: A retrospective study. Indian Journal of Dermatology, Venereology and Leprology, 81(6), 584–587. https://doi.org/10.4103/0378-6323.168329

Damiani, G., Bragazzi, N. L., Karimkhani Aksut, C., Wu, D., Alicandro, G., McGonagle, D., Guo, C., Dellavalle, R., Grada, A., Wong, P., La Vecchia, C., Tam, L. S., Cooper, K. D., & Naghavi, M. (2021). The Global, Regional, and National Burden of Psoriasis: Results and Insights From the Global Burden of Disease 2019 Study. Frontiers in Medicine, 8(December). https://doi.org/10.3389/fmed.2021.743180

Dayal, S., Kaura, R., Sahu, P., & Jain, V. K. (2018). Tazarotene gel with narrow-band UVB phototherapy: A synergistic combination in psoriasis. Anais Brasileiros de Dermatologia, 93(3), 385–390. https://doi.org/10.1590/abd1806-4841.20186723

Elmets, C. A. (2023). UVB phototherapy (broadband and narrowband). UVB Phototherapy (Broadband and Narrowband). https://www.uptodate.com/contents/uvb-phototherapy-broadband-and-narrowband

Esen Salman, K., Kivanç Altunay, İ., & Salman, A. (2019). The efficacy and safety of targeted narrowband UVB therapy: A retrospective cohort study. Turkish Journal of Medical Sciences, 49(2), 595–603. https://doi.org/10.3906/sag-1810-110

Eysteinsdóttir, J. H., Ólafsson, J. H., Agnarsson, B. A., Lúdvíksson, B. R., & Sigurgeirsson, B. (2014). Psoriasis treatment: Faster and long-standing results after bathing in geothermal seawater. A randomized trial of three UVB phototherapy regimens. Photodermatology Photoimmunology and Photomedicine, 30(1), 25–34. https://doi.org/10.1111/phpp.12090

Farahnik, B., Patel, V., Beroukhim, K., Hao Zhu, T., Abrouk, M., Nakamura, M., Singh, R., Lee, K., Bhutani, T., & Koo, J. (2016). Combining biologic and phototherapy treatments for psoriasis: safety, efficacy, and patient acceptability. Psoriasis: Targets and Therapy, Volume 6, 105–111. https://doi.org/10.2147/ptt.s98952

Kim, W. B., Jerome, D., & Yeung, J. (2017). Diagnosis and management of psoriasis. Pubmed, 63(4), 278–285. https://pubmed.ncbi.nlm.nih.gov/28404701/

Kragballe, K., Hölzle, E., Kerkhof, P. C. M. van de, & Philipp, S. (2014). Treatment of plaque psoriasis. Wiley. https://onlinelibrary.wiley.com/doi/10.1002/9781118661796.ch17

Li, Y., Cao, Z., Guo, J., Li, Q., Zhu, W., Kuang, Y., & Chen, X. (2022). Assessment of efficacy and safety of UV-based therapy for psoriasis: a network meta-analysis of randomized controlled trials. In Annals of Medicine (Vol. 54, Issue 1, pp. 159–169). Taylor and Francis Ltd. https://doi.org/10.1080/07853890.2021.2022187

Lynch, M., Malara, A., Timoney, I., Vencken, S., Ahern, T., Awdeh, F., Sweeney, C., Galligan, M., Kelly, G., Hughes, R., Murad, A., Hambly, R., O’shea, D., Doran, P., & Kirby, B. (2022). Sitagliptin and Narrow-Band Ultraviolet-B for Moderate Psoriasis (DINUP): A Randomised Controlled Clinical Trial. Dermatology, 238(1), 140–147. https://doi.org/10.1159/000514494

Manchanda Yashpal, De Abhishek, Das Sudip, & Chakraborty Disha. (2023). Disease Assessment in Psoriasis. Indian Journal of Dermatology, 68(3), 278–281. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10389140/

Matos, T. R., Ling, T. C., & Sheth, V. (2016a). Ultraviolet B radiation therapy for psoriasis: Pursuing the optimal regime. Clinics in Dermatology, 34(5), 587–593. https://doi.org/10.1016/j.clindermatol.2016.05.008

Matos, T. R., Ling, T. C., & Sheth, V. (2016b). Ultraviolet B radiation therapy for psoriasis: Pursuing the optimal regime. Clinics in Dermatology, 34(5), 587–593. https://doi.org/10.1016/j.clindermatol.2016.05.008

Morita, A., Yamaguchi, Y., Tateishi, C., Ikumi, K., Yamamoto, A., Nishihara, H., Hayashi, D., Watanabe, Y., Watanabe, Y., Maruyama, A., Masuda, K., Tsuruta, D., & Katoh, N. (2022). Efficacy and safety of apremilast and phototherapy versus phototherapy only in psoriasis vulgaris. Journal of Dermatology, 49(12), 1211–1220. https://doi.org/10.1111/1346-8138.16566

Nair, R. V., & Jayapalan, S. (2015). Narrowband UVB phototherapy and PUVA photochemotherapy in psoriasis vulgaris. Clinical Epidemiology and Global Health, 3, S75–S79. https://doi.org/10.1016/j.cegh.2015.10.004

Naufal, ad, Hary Kusumastuti, E., & Nurul Hidayati, A. (2021). Risk Factor Profile and Quality of Life of Psoriasis Vulgaris. https://e-journal.unair.ac.id/BIKK/article/view/26056/pdf )

Ngao, K., & Udey, M. (2019). Fitzpatrick’s Dermatology (9th ed., Vol. 1). Mc Graw Hill.

Odrzywołek, W., Deda, A., Zdrada-Nowak, J., Błońska-Fajfrowska, B., Wcisło-Dziadecka, D., & Wilczyński, S. (2023). Effect of Narrow-Band Ultraviolet B Therapy of Psoriasis Vulgaris on Skin Directional Reflectance, Skin Density and Epidermal Thickness. Applied Sciences (Switzerland), 13(16). https://doi.org/10.3390/app13169311

Parlak, N., Kundakci, N., Parlak, A., & Akay, B. N. (2015). Narrowband ultraviolet B phototherapy starting and incremental dose in patients with psoriasis: Comparison of percentage dose and fixed dose protocols. Photodermatology Photoimmunology and Photomedicine, 31(2), 90–97. https://doi.org/10.1111/phpp.12152

Philipp, S. (2014). Therapeutic aim of psoriasis therapy. Wiley. https://onlinelibrary.wiley.com/doi/abs/10.1002/9781118661796.ch16

Polańska, A., Gaura, T., Bowszyc-Dmochowska, M., Osmola-Mańkowska, A., Olek-Hrab, K., Adamski, Z., Żaba, R., & Dańczak-Pazdrowska, A. (2019). Calcipotriol/betamethasone ointment compared to narrow-band UVB in plaque psoriasis: first clinical and ultrasonographic study. International Journal of Dermatology, 58(1), 108–113. https://doi.org/10.1111/ijd.14150

Purnama Sari, D., Hany, A., Christanti, M. A., & Amalia, A. T. (2022). Correlation between Perception with The Needs of Structured Education for Psoriasis Patients during The Pandemic of COVID-19. Article in Journal of Nursing Science Update. https://doi.org/10.21776/ub.jik.2022.010.01.3

Rendon, A., & Schäkel, K. (2019). Psoriasis pathogenesis and treatment. In International Journal of Molecular Sciences (Vol. 20, Issue 6). MDPI AG. https://doi.org/10.3390/ijms20061475

Ryu, H. H., Choe, Y. S., Jo, S., Youn, J. Il, & Jo, S. J. (2014). Remission period in psoriasis after multiple cycles of narrowband ultraviolet B phototherapy. Journal of Dermatology, 41(7), 622–627. https://doi.org/10.1111/1346-8138.12541

Salgado-Boquete, L., Carrascosa, J. M., Llamas-Velasco, M., Ruiz-Villaverde, R., de la Cueva, P., & Belinchón, I. (2021). A new classification of the severity of psoriasis: What’s moderate psoriasis? Life, 11(7). https://doi.org/10.3390/life11070627

Van, T. N., Hoang Van, T., Thi Minh, P. P., Nguyen Trong, H., Chau Van, T., Dinh Huu, N., Pham Thi, T., Thi Thu, H. Do, Tran Cam, V., Le Huyen, M., Tran Hau, K., Gandolfi, M., Satolli, F., Feliciani, C., Tirant, M., Vojvodic, A., & Lotti, T. (2019). Efficacy of narrow - band UVB phototherapy versus PUVA chemophototherapy for psoriasis in Vietnamese patients. Open Access Macedonian Journal of Medical Sciences, 7(2), 227–230. https://doi.org/10.3889/oamjms.2019.057

Zhu, B., Jing, M., Yu, Q., Ge, X., Yuan, F., & Shi, L. (2022). Treatments in psoriasis: from standard pharmacotherapy to nanotechnology therapy. In Advances in Dermatology and Allergology (Vol. 39, Issue 3, pp. 460–471). Termedia Publishing House Ltd. https://doi.org/10.5114/ada.2021.108445

Downloads

Published

2024-06-30

How to Cite

Rahmawati, H. R. . (2024) “The effectiveness of narrowband ultraviolet b phototherapy for the treatment of moderate to severe psoriasis in adult patients ”, Science Midwifery, 12(2), pp. 850–863. doi: 10.35335/midwifery.v12i2.1517.