The relationship between q-SOFA score and mortality of sepsis patients at Jogja Hospital
DOI:
https://doi.org/10.35335/midwifery.v12i4.1712Keywords:
ICU, Mortality, q-SOFA, SepsisAbstract
Sepsis and severe sepsis are the leading causes of death in critically ill patients admitted to intensive care units (ICUs) in the United States. The national economic burden for sepsis in Indonesia at 100,000 patients is estimated to reach USD 130 million. Currently, screening for patients who may have sepsis has also been used frequently. The assessment can be done with a qSOFA score measurement (quick SOFA) or rapid measurement. This study used a retrospective with secondary data from medical records of patients treated in the intensive care unit of Jogja Hospital from January through December 2023. The subjects of 62 patients suffering from sepsis were obtained, with 25 patients (40.3%) at low-risk qSOFA values and 37 (59.7%) at high-risk qSOFA values. The results of this study stated that there was no relationship between the patient's qSOFA score when admitted to the hospital and the mortality of sepsis patients in the intensive care unit of the Jogja Hospital (p>0.07). Thus, the results of this study provide important insights for clinical practitioners in evaluating and planning the treatment of sepsis patients, considering that qSOFA, although useful as an initial screening tool, should not be used as the sole factor in clinical decision-making regarding the management of sepsis patients.
Downloads
References
Abou Dagher, G., Harmouche, E., Jabbour, E., Bachir, R., Zebian, D., & Bou Chebl, R. (2015). Sepsis in hemodialysis patients. BMC Emergency Medicine, 15(1), 30. https://doi.org/10.1186/s12873-015-0057-y
Askim, Å., Moser, F., Gustad, L. T., Stene, H., Gundersen, M., Åsvold, B. O., Dale, J., Bjørnsen, L. P., Damås, J. K., & Solligård, E. (2017). Poor performance of quick-SOFA (qSOFA) score in predicting severe sepsis and mortality – a prospective study of patients admitted with infection to the emergency department. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 25(1), 56. https://doi.org/10.1186/s13049-017-0399-4
Dellinger, R. P., Levy, M. M., Rhodes, A., Annane, D., Gerlach, H., Opal, S. M., Sevransky, J. E., Sprung, C. L., Douglas, I. S., Jaeschke, R., Osborn, T. M., Nunnally, M. E., Townsend, S. R., Reinhart, K., Kleinpell, R. M., Angus, D. C., Deutschman, C. S., Machado, F. R., Rubenfeld, G. D., … Moreno, R. (2013). Surviving Sepsis Campaign. Critical Care Medicine, 41(2), 580–637. https://doi.org/10.1097/CCM.0b013e31827e83af
Donnelly, J. P., Safford, M. M., Shapiro, N. I., Baddley, J. W., & Wang, H. E. (2017). Application of the Third International Consensus Definitions for Sepsis (Sepsis-3) Classification: a retrospective population-based cohort study. The Lancet Infectious Diseases, 17(6), 661–670. https://doi.org/10.1016/S1473-3099(17)30117-2
Epstein, L., Dantes, R., Magill, S., & Fiore, A. (2016). Varying Estimates of Sepsis Mortality Using Death Certificates and Administrative Codes  United States, 1999–2014. MMWR. Morbidity and Mortality Weekly Report, 65(13), 342–345. https://doi.org/10.15585/mmwr.mm6513a2
Ersyaputri, N. (2023). PROGNOSIS PASIEN SEPSIS BERDASARKAN NILAI NEUTROPHIL-LYMPHOCYTE RATIO, MONOCYTE-LYMPHOCYTE RATIO, DAN THROMBOCYTE-LYMPHOCYTE RATIO: Penelitian di ICU RSUD Raden Mattaher Jambi Tahun 2023.
Habiburrahman, M., & Putra, A. B. (2023). Manajemen Komprehensif Sepsis Akibat Infeksi Saluran Kemih pada Kehamilan. Cermin Dunia Kedokteran, 50(6), 311–320.
Hartanto, B., & Zulfariansyah, A. (2020). Laporan Kasus: Tata Laksana Sepsis Bundle pada Pasien Syok Sepsis dengan Perforasi Gaster. In Majalah Anestesia & Critical Care (Vol. 38, Issue 1).
Idris, F. (2018). KORELASI KADAR GALECTIN-3 DENGAN BERATNYA DERAJAT KLINIS BERDASARKAN SKOR SOFA PADA PASIEN SEPSIS CORRELATION OF GALECTIN-3 LEVELS WITH CLINICAL SEVERITY ACCORDING TO SOFA SCORE IN SEPSIS PATIENTS. Universitas Hasanuddin.
Irvan, I., Febyan, F., & Suparto, S. (2018). Sepsis dan Tata Laksana Berdasar Guideline Terbaru. JAI (Jurnal Anestesiologi Indonesia), 10(1), 62. https://doi.org/10.14710/jai.v10i1.20715
Koch, C., Edinger, F., Fischer, T., Brenck, F., Hecker, A., Katzer, C., … Schneck, E. (2020). Comparison of qSOFA score, SOFA score, and SIRS criteria for the prediction of infection and mortality among surgical intermediate and intensive care patients. World Journal of Emergency Surgery, 15, 1–10.
Li, A., Ling, L., Qin, H., Arabi, Y. M., Myatra, S. N., Egi, M., Kim, J. H., Nor, M. B. M., Son, D. N., Fang, W.-F., Wahyuprajitno, B., Hashmi, M., Faruq, M. O., Patjanasoontorn, B., Al Bahrani, M. J., Shrestha, B. R., Shrestha, U., Nafees, K. M. K., Sann, K. K., … Tuân, N. ÄÂÂ. (2024). Prognostic evaluation of quick sequential organ failure assessment score in ICU patients with sepsis across different income settings. Critical Care, 28(1), 30. https://doi.org/10.1186/s13054-024-04804-7
Liao, K.-M., Lin, T.-C., Li, C.-Y., & Yang, Y.-H. K. (2015). Dementia Increases Severe Sepsis and Mortality in Hospitalized Patients with Chronic Obstructive Pulmonary Disease. Medicine, 94(23), e967. https://doi.org/10.1097/MD.0000000000000967
Purba, A. K. R., Mariana, N., Aliska, G., Wijaya, S. H., Wulandari, R. R., Hadi, U., Hamzah, Nugroho, C. W., van der Schans, J., & Postma, M. J. (2020). The burden and costs of sepsis and reimbursement of its treatment in a developing country: An observational study on focal infections in Indonesia. International Journal of Infectious Diseases, 96, 211–218. https://doi.org/10.1016/j.ijid.2020.04.075
Purwanto, D. S., & Astrawinata, D. A. W. (2018). Mekanisme Kompleks Sepsis dan Syok Septik. Jurnal Biomedik (JBM), 10(3), 143. https://doi.org/10.35790/jbm.10.3.2018.21979
Putra, I. A. S. (2019). Update Tatalaksana Sepsis. Cermin Dunia Kedokteran, 46(11). https://doi.org/DOI: https://doi.org/10.55175/cdk.v46i11.408
Putra, I. M. P. (2018). Pendekatan Sepsis dengan Skor SOFA. Cermin Dunia Kedokteran, 45(8). https://doi.org/DOI: https://doi.org/10.55175/cdk.v45i8.740
Putra, I. A. S. (2019). Update tatalaksana sepsis. Cermin Dunia Kedokteran, 46(11), 681–685.
Saraswati, D. D., Pudjiadi, A. H., Djer, M. M., Supriyatno, B., Syarif, D. R., & Kurniati, N. (2016). Faktor risiko yang berperan pada mortalitas sepsis. Sari Pediatri, 15(5), 281–288.
Sari, C. E. D. (2023). HUBUNGAN PARAMETER LABORATORIUM DENGAN LAMA RAWAT INAP PADA PASIEN DEMAM BERDARAH DENGUE Studi Observasional Analitik pada pasien rawat inap di RSUD Bayung Lencir Kabupaten Musi Banyuasin. Universitas Islam Sultan Agung Semarang.
Sari, E. K. (2019). Tinjauan Literatur: Perbandingan qSOFA dan SIRS dalam Mengidentifikasi Pasien dengan Sepsis dan Memprediksi Mortalitasnya: Review Artikel. Majalah Kesehatan, 6(4), 277–285. https://doi.org/10.21776/ub.majalahkesehatan.2019.006.04.7
Tiwari, A. K., Jamshed, N., Sahu, A. K., Kumar, A., Aggarwal, P., Bhoi, S., Mathew, R., & Ekka, M. (2023). Performance of qSOFA Score as a Screening Tool for Sepsis in the Emergency Department. Journal of Emergencies, Trauma, and Shock, 16(1), 3–7. https://doi.org/10.4103/jets.jets_99_22
Vivianni, A., & Farhanah, N. (2016). Faktor – Faktor Prediktor Mortalitas Sepsis dan Syok Sepsis di ICU RSUP dr Kariadi. Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal), 5(4), 504–517. https://doi.org/https://doi.org/10.14710/dmj.v5i4.14246
Wiriansya, E. P., Devi Grania Amalia, Andi Husni Tanra, & Julia. (2022). Manajemen Terapi Cairan pada Sepsis. Fakumi Medical Journal: Jurnal Mahasiswa Kedokteran, 2(6), 393–407. https://doi.org/10.33096/fmj.v2i6.18
Wati, D. K., Hartawan, I. N. B., Suparyatha, I. B. G., Mahalini, D. S., & Pratiwi IGAPE, U. I. (2019). Profil Sepsis Anak di Pediatric Intensive Care Unit Rumah Sakit Umum Pusat Sanglah Denpasar-Bali. Sari Pediatri, 21(3), 152–158.
