Analysis of factors associated with the onset of preeclampsia in pregnant women in Kotabaru District, South Kalimantan Province
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Apr 24, 2025
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Abstract
Background: South Kalimantan with an MMR of 145 deaths per 100,000 KH. The number of maternal deaths due to preeclampsia is 10 cases. Kotabaru with the second highest number of maternal deaths with a total of 14 cases and there were 6 cases in 2023. Early-onset preeclampsia is preeclampsia that occurs before 34 weeks of gestation and late-onset preeclampsia. The aim of the study was to analyse the correlation of risk factors with the onset of preeclampsia in pregnant women in Kotabaru District. Research Methods: Analytical observational research with cross sectional research design after obtaining approval from the ethics commission of Stikes Guna Bangsa Yogjakarta No. 023/KEPK/IX/2024. All preeclampsia pregnant women in 2023 as many as 148 preeclampsia pregnant women's data were taken and recorded, then chi squared analysis and multiple logistic regression were carried out. Results: The results showed there was an association between parity (p value = 0.001), BMI (p value = 0.017), multiple pregnancy (p value = 0, 025) with the onset of preeclampsia. The results of multiple logistic regression analysis showed the variable parity p value = 0.001 and Exp B (3, 975) and 95% CI 1.811 - 8.401 is the most dominant factor associated with the onset of preeclampsia. Conclusion: There is an association between parity, BMI, and multiple pregnancy with the onset of preeclampsia. The most dominant factor associated is parity. The implications of the research results are that the community is more active in participating in maternal and child health programs, and disseminating information about preeclampsia to other pregnant women, providing iron-enriching and providing calcium tablets to mothers from the first trimester of pregnancy if they are anemic, integrated ANC services.
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How to Cite
Arianti, D., Yuliani, I., Risnawati, R., Maimunah, S. and Gunarmi, G. (2025) “Analysis of factors associated with the onset of preeclampsia in pregnant women in Kotabaru District, South Kalimantan Province”, Science Midwifery, 13(1), pp. 296-303. doi: 10.35335/midwifery.v13i1.1878.
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Alanazi, A. S., Victor, F., Rehman, K., Khan, Y. H., Yunusa, I., Alzarea, A. I., Akash, M. S. H., & Mallhi, T. H. (2022). Pre-Existing Diabetes Mellitus, Hypertension and KidneyDisease as Risk Factors of Pre-Eclampsia: A Disease of Theories and Its Association with Genetic Polymorphism. International Journal of Environmental Research and Public Health, 19(24). https://doi.org/10.3390/ijerph192416690
Chappell, L. C., Cluver, C. A., Kingdom, J., & Tong, S. (2021). Pre-eclampsia. The Lancet, 398(10297), 341–354. https://doi.org/10.1016/S0140-6736(20)32335-7
Cheng, S. Bin, Nakashima, A., & Sharma, S. (2023). Understanding Pre-Eclampsia Using Alzheimer’s Etiology: An Intriguing Viewpoint. American Journal of Reproductive Immunology, 75(3), 372–381. https://doi.org/10.1111/aji.12446
Cornelius, D. C. (2018). Preeclampsia: From inflammation to immunoregulation. Clinical Medicine Insights: Blood Disorders, 11. https://doi.org/10.1177/1179545X17752325
Dana, B., Agustina, D., & Ramadhani, I. (2024). The relationship between mother ’ s age and parity and the incident of hypertension in pregnant women at Kayuagung Hospital year 2022. 12(3).
Fadli, F. (2019). Bunga Rampai: Apa itu Psikopatologi? “Rangkaian Catatan Ringkas Tentang Gangguan Jiwa.” Unimal Press, 53(9), 1–158.
Fatimah, & Nuryaningsih. (2018). Buku Ajar Asuhan Kebidanan Pada Kelompok Rentan.
Fox, N. S., Roman, A. S., Saltzman, D. H., Hourizadeh, T., Hastings, J., & Rebarber, A. (2014). Risk factors for preeclampsia in twin pregnancies. American Journal of Perinatology, 31(2), 163–166. https://doi.org/10.1055/s-0033-1343775
Ives, C. W., Sinkey, R., Rajapreyar, I., Tita, A. T. N., & Oparil, S. (2020). Preeclampsia—Pathophysiology and Clinical Presentations: JACC State-of-the-Art Review. Journal of the American College of Cardiology, 76(14), 1690–1702. https://doi.org/10.1016/j.jacc.2020.08.014
Lopez-Jaramillo, P., Barajas, J., Rueda-Quijano, S. M., Lopez-Lopez, C., & Felix, C. (2018). Obesity and Preeclampsia: Common Pathophysiological Mechanisms. Frontiers in Physiology, 9(December), 1–10. https://doi.org/10.3389/fphys.2018.01838
Lushinta, L., Patty, F. I. T., Virawati, D. I., & Anggraini, E. (2022). The Effect of Assessment Mean Arterial Pressure and Body Mass Index as an Early Detection of Pre-Eclampsia. Jurnal Kebidanan, 12(2), 136–143. https://doi.org/10.31983/jkb.v12i2.9207
Mazumder, H., Rimu, F. H., Shimul, M. H., Das, J., Gain, E. P., Liaw, W., & Hossain, M. M. (2024). Maternal health outcomes associated with ambient air pollution: An umbrella review of systematic reviews and meta-analyses. Science of The Total Environment, 914, 169792. https://doi.org/https://doi.org/10.1016/j.scitotenv.2023.169792
Parantika, R. W., Hardianto, G., Miftahussurur, M., & Anis, W. (2021). Relationship Between Obesity, Twin-Pregnancy and Previous History of Preeclampsia With Preeclampsia. Indonesian Midwifery and Health Sciences Journal, 5(3), 307–316. https://doi.org/10.20473/imhsj.v5i3.2021.307-316
Paré, E., Parry, S., Mcelrath, T., Pucci, D., Newton, A., & Lim, K.-H. (2014). Clinical Risk Factors for Preeclampsia in the 21st Century. Obstetrics and Gynecology, 124. https://doi.org/10.1097/AOG.0000000000000451
Poniedziałek-Czajkowska, E., Mierzyński, R., & Leszczyńska-Gorzelak, B. (2023). Preeclampsia and Obesity—The Preventive Role of Exercise. International Journal of Environmental Research and Public Health, 20(2). https://doi.org/10.3390/ijerph20021267
Profil Dinas Kesehatan Kabupaten Kotabaru. (2023). Angka Kematian Ibu di Kabupaten Kota Baru.
Profil Dinas Kesehatan Kalimantan Selatan. (2024). Angka Kematian Ibu Di Kalimantan Selatan.
Rahayu, B. (2023). Hubungan Kehamilan Ganda dengan Kejadian Preeklampsia. Oksitosin : Jurnal Ilmiah Kebidanan, 10(2), 98–103. https://doi.org/10.35316/oksitosin.v10i2.2430
Shaikh, N., Nahid, S., Ummunnisa, F., Gul, A., Basha, A. Al, Yahia, W., Hail, F. Al, Elfil, H., Abdulla, E., Nainthramveetil, M. M., Zubair, M., Khan, S., korichi, N., Alkhawaga, S., Ismail, H., & Yaqoob, S. (2021). Preeclampsia: From Etiopathology to Organ Dysfunction (H. S. Abduljabbar (ed.)). IntechOpen. https://doi.org/10.5772/intechopen.101240
Soultoni Akbar, P., Irene Putri, S., & Zainol Rachman, M. (2022). an Analysis of Maternal Mortality Causes in Indonesia. The 9th International Conference on Public Health, 292–298. https://doi.org/10.26911/FP.ICPH.09.2022.14
Sutni, A., Jasmawati, J., & Nulhakim, L. (2023). the Relationship Between Anemia Incidence in Pregnant Mothers and Low Birth Weight Baby Delivery. International Journal of Nursing and Midwifery Science (Ijnms), 7(2A), 72–79. https://doi.org/10.29082/ijnms/2023/vol7/iss2a/494
Syahadatina, M., Santoso, B., Triawanti, Rahardjo, B., Aditiawarman, Harjanto, & Purwanto, B. (2021). Konsep Preeklamsia : Patomekanise Dan Pencegahan.
Syairaji, M., Nurdiati, D. S., Wiratama, B. S., Prüst, Z. D., Bloemenkamp, K. W. M., & Verschueren, K. J. C. (2024). Trends and causes of maternal mortality in Indonesia: a systematic review. BMC Pregnancy and Childbirth, 24(1), 1–14. https://doi.org/10.1186/s12884-024-06687-6
Tarigan, R. A., & Yulia, R. (2021). Parity Relationship With the Occurrence of Preeclampsia in Pregnant Women Hubungan Paritas Dengan Kejadian Preeklampsia Pada Ibu Hamil. Journal of Health |, 105.
Torres-Torres, J., Espino-y-Sosa, S., Martinez-Portilla, R., Borboa-Olivares, H., Estrada-Gutierrez, G., Acevedo-Gallegos, S., Ruiz-Ramirez, E., Velasco-Espin, M., Cerda-Flores, P., Ramirez-Gonzalez, A., & Rojas-Zepeda, L. (2024). A Narrative Review on the Pathophysiology of Preeclampsia. International Journal of Molecular Sciences, 25(14), 1–24. https://doi.org/10.3390/ijms25147569
Wahyuni, C. A. E. R. I. I. L. (2024). Determinan Kejadian Preeklampsia di RSUD Dr. H. Yuliddin Away Tapaktuan. Journal Of Healthcare Technology And Medicine, Vol 10, No 1 (2024): April 2024, 168–178. http://jurnal.uui.ac.id/index.php/JHTM/article/view/3812/1871
WHO. (2025). Maternal mortality. https://www.who.int/news-room/fact-sheets/detail/maternal-mortality