THE EFFECT OF APPLYING VITAMIN D ONREPAIRING OF THORAX PHOTO OF TUBERCULOSIS PATIENTS OF BATAK ETHNIC IN MEDAN

Authors

  • Seri Rayani Bangun STIKes Santa Elisabeth Medan
  • Bintang Y.K. Sinaga Departemen Pulmonology and Respiratory Medicine, University of North Sumatera
  • Nasipta Ginting STIKes Santa Elisabeth Medan

Keywords:

Levels of Vitamin D, Thorax Photo Fix

Abstract

This study aims to determine the effect of vitamin D on the repairingof thoracic on patients with pulmonary tuberculosis of Batak ethnic in Medan, conducted on 42 patients with TB, vitamin D group of 21 people and 21 placebo. Giving vitamin D dose of 2.5 mg (100,000 IU) for 4 times (weeks 0, 2, 4, 6) and placebo for 4 times (weeks 0, 2, 4, 6). B. The assessment of vitamin D and thorax photo were done before and after intervention.The results showed that the levels of vitamin D results before and after there is a difference, the measurement results using the enzyme linked immunosorbent assay (ELISA) provisions of the absorbance of each well at a wavelength of 450 ± 10 nm.Vitamin D levels were measured 25 (OH) D nmol / L then further analyzed using paired T test on vitamin D group p = 0:00, mean difference 29.27 + vitamin D levels were 22 ng / ml, whereas the placebo group p = 0:27, the difference of the mean levels of vitamin D 1:36 + 5:53 ng / ml. After examination of thorax photo in hospital then analyzed using Chi-square test. Vitamin D group showed a total improvement (66.7%) while the placebo treatment (33.3%), p = 0:06 concluded there was no effect of vitamin D on the restoration of thorax photo on patients pulmonary tuberculosis Batak ethnic.

Downloads

Download data is not yet available.

References

Basir D, Yani FF. Tuberkulosis dengan Keadaan Khusus. 2012. Buku Ajar Respirologi Anak. Fakultas Kedokteran Universitas Indonesia. Jakarta,:. p. 228-45

Tabrani Rab. 2010. Ilmu Penyakit Paru. Editor sandy qlintang diterbitkan oleh hipokrates; 157-168

Halim Danusantoso. 2012. Buku saku penyakit paru. jakarta. Edisi 2. EGC.

Bambang Ruswanto, Nurjazuli, Mursid Raharj. 2012. Analisis Spasial Sebaran Kasus Tuberkulosis Paru Ditinjau Dari Faktor Lingkungan Dalam dan Luar Rumah di Kabupaten Pekalongan . Vol. 11 No. 1, 22-28

WHO, 2014. Global Tuberculosis Report 2014; 13-61. Tersedia di http://www.who.int/TB/data. Diakses 29 November 2014

Profil kesehatan provinsi sumatera utara tahun 2012

Liu PT, Stenger S, Li H et al. 2006. Sciencexpress. Toll Like Receptor Triggering of a Vitamin D-Mediated Human Antimicrobial Response. 24:1770-1773

Dini, C and Bianchi, A. 2012. The potential role of vitamin D for prevention and treatment of tuberculosis and infectious diseases Ann Ist Super Sanità. Italy.; 319-327

Siswanto, at al. 2009. Jurnal Kedokteran Brawijaya, Vitamin D as Supportive Treatment Improve The Sputum Conversion and Radiographic Finding in Tuberculosis Patients. Vol. XXV, No. 3, Desember 2009; 128-132

Martineau AR, Honecker FU, Wilkinson RJ, Griffiths CJ. 2007. Journal of Steroid Biochemistry & Molecular Biology. Vitamin D in the treatment of pulmonary tuberculosis.103;793–8

Martineau AR, at al. 2011. High-dose vitamin D3 during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial. Centre for Health Sciences Barts dan The London School of Medicine and Dentistry Lancet.; 377: 242-50

Hemant K Bid, Dhruva K Mishra, Rama D Mittal. 2005. Asian Pasific Journal of cancer prevention. Vitamin-D Receptor (VDR) Gene (Fok-I, Taq-I & Apa-I) Polymorphisms in Healthy Individuals from North Indian Population. volume 6. edisi 2; 147-152

Shaden, Haddad. 2014. Meta Gene, Syria. Vitamin-D receptor (VDR) gene polymorphisms (Taq-I & Apa-I) in Syrian healthy population ; 646–650

Salahuddin N, Ali F, Hasan Z, Rao N, Aqeel M, Mahmood F. 2013. Vitamin D accelerates clinical recovery from tuberculosis: results of the SUCCINCT Study [Supplementary Cholecalciferol in recovery from tuberculosis]. A randomized, placebo-controlled, clinical trial of vitamin D supplementation in patients with pulmonary tuberculosis. BMC Infectious Disease.; 13-22

Badan Pusat Statistik Provinsi Sumatera Utara. 2013. Jurnal Kesehatan Lingkungan Indonesia. Sumatera Utara dalam Angka 2013/ Sumatera Utara in Figures 2013. Madan

Arbeitsanleitung/Manual. Valid from 17.01.2012. 25(OH)-Vitamin D direct ELISA Kit For the determination of 25(OH)-Vitamin D in human serum. Immundiagnostik AG Stubenwald-Allee 8a D-64625 Bensheim

https://Kebudayaanindonesia.net/kebudayaan/952/suku-batak-sumatera-utara diakses pada tanggal 20 Agustus

Gao L, Tao Y, Zhang L, Jin Q. Vitamin D Receptor Genetics Polymorphisms and Tuberculosis: Update Systemic review and meta-analysis. International Journal of Tuberculosis Lung Disease. 2010; 14 (1): 15-23

Keflie, M.Sc. Vitamin D deficiencies among tuberculosis patients in Africa: A systematic review. Nutrition 31, review, Elsevier 2015; p.1204-1212

Junaid, Kashaf et al. High prevalence of vitamin D deficiency among women of child-bearing age in Lahore Pakistan, associating with lack of sun exposure and illiteracy. BMC Women’s Health. 2015; p. 1-8

Chan TY, Poon P, Pang J, Swaminathan R, Chan CH, Nisar M, Williams CS, Davies PD. A Study of Calcium and Vitamin D Metabolism in Chinese Patients With Pulmonary Tuberculosis. J Trop Med Hyg. 1994 Feb; 97(1): 26-30

Downloads

Published

2021-09-02

How to Cite

Bangun, S. R., Sinaga , B. Y. and Ginting, N. . (2021) “THE EFFECT OF APPLYING VITAMIN D ONREPAIRING OF THORAX PHOTO OF TUBERCULOSIS PATIENTS OF BATAK ETHNIC IN MEDAN”, Science Midwifery, 10(1, October), pp. 64–71. Available at: https://midwifery.iocspublisher.org/index.php/midwifery/article/view/141 (Accessed: 20 April 2026).